Aside

View this resume online

Contact

Programming Skills

R
Bash
Python
Web Development
SQL

Other Skills

Highly experienced in:

Motivated and collaborative, recently involved in Machine Learning, NGS data analysis, UK Biobank and genomics prediction

More info

See full CV at ruizsergio.com/cv for a complete list of positions, publications and more


Reference contact details provided upon request

Disclaimer

photo

Source code available in github

Last updated on Oct 8, 2021

Main

Sergio Ruiz-Carmona

I am currently a Research Officer and Bioinformatician at the Baker Institute, under the supervision of professor Mike Inouye. My research interests are broad and involve mainly the relationship between genetic variants and their effect on protein structures.

I carried out my MSc and PhD in Barcelona in the Barril Lab, where I worked with different structure-based drug design methods with the aim to improve drug design for non-standard targets.

Selected Education

PhD in Biomedicine

Universitat de Barcelona

Barcelona, ES

2017 - 2012

  • Virtual Screening for novel MoA: Apps. and method developments
  • Development and application of structure-based drug discovery methods
  • Awards: Extraordinary prize for PhD Thesis and Ramon Margalef award for best publication

Selected Positions

Research Officer and Bioinformatician

Inouye Lab
Baker Heart and Diabetes Institute

Melbourne, AU

Today - 2019

  • I am working in a project that overlaps Structural Biology and Genomics, in collaboration with David Ascher’s Lab. Mainly, I am trying to understand how rare missense variants alter protein structures and can induce disease

Associate Professor

Faculty of Pharmacy, Universitat de Barcelona

Barcelona, ES

2019 - 2015

  • Classes in Pharmacy, Food Science and Nutrition degrees (total 400h)

Postdoctoral Researcher

Barril Lab, Universitat de Barcelona

Barcelona, ES

2018 - 2017

  • After finishing my PhD, I worked in exciting collaborative projects in the field of epigenetics and cancer, where I carried out multidisciplinary research and learned new experimental skills

EMBO Short-Term Fellow

Andreas Bender Lab, Unversity of Cambridge

Cambridge, GB

2017

  • I spent 2 months in one of the main Pharmacogenomics groups in the world, where I used gene-expression profiles of different biological systems to study BRD4 and drug selectivity

Skills and Training

Computational Techniques

Computer-Aided Drug Discovery (SBDD), Machine Learning, Virtual Screening, Docking, Molecular Dynamics, Chemoinformatics, Quantum Chemistry, Bioinformatics Tools and Analysis

N/A

N/A

Programming

R, Python, Perl, C++, LaTeX, Bash, Java, MySQL, HTML and Android and Web Development

N/A

N/A

Management Skills

2021 EMBO Practical Course: Research to service: Planning and running a bioinformatics core facility

N/A

N/A

Outreach and other activities

Australasian Leadership Computing Grants

Story about NCI Computing Grant

N/A

2021 - 2020

  • Together with Mike Inouye, we were awarded a 1 year computing grant by the Australian National Compuational Infrastructure to study COVID-19 proteins and possible drug treatments

Shiny App development

Related to a project we published in the Journal Circulation

N/A

2021

New tools for new medicines, The Conversation article

Lay-summary of some of my work and opinion for The Conversation Spain

N/A

2021

COVID-19 daily dashboard, until Nov 2020

Personal project to showcase COVID-19 evolution in Victoria during major lockdown in 2020

N/A

2020

I have been involved in more than 10 collaborative projects in very different fields. I enjoy helping other researchers and collaborators to work in common scientific challenges

Main Scientific Output

My ultimate goal is to help patients: from drug discovery to precision medicine and hospital care data analysis

Oxygen Pathway Limitations in Patients with Chronic Thromboembolic Pulmonary Hypertension

Circulation
Read it here

N/A

2021

  • Erin J Howden *, Sergio Ruiz-Carmona *, […] Andre La Gerche, Marion Delcroix and Guido Claessen
  • Result of a Bioinformatics Core collaboration. Shiny app developed

The carbon footprint of bioinformatics

bioRxiv
Read it here

N/A

2021

  • Jason G Grealey, […] Sergio Ruiz Carmona , Michael Inouye

Dynamic undocking and the quasi-bound state as tools for drug discovery

Nature Chemistry
Read it here

N/A

2017

  • Sergio Ruiz-Carmona, P Schmidtke, […] Rod Hubbard and Xavier Barril
  • Highlighted in its issue cover

rDock: a fast, versatile and open source program for docking ligands to proteins and nucleic acids

PLoS Computational Biology
Read it here

N/A

2014

  • Sergio Ruiz-Carmona, Daniel Alvarez-Garcia, […] Xavier Barril, Rod Hubbard and S David Morley